A year after the death of his friend and partner Sherlock Holmes, Dr. John Watson resumes his medical career at a clinic dedicated to the treatment of rare diseases. However, he soon finds that his old life is not done with him yet.

Brought together by a midnight phone call, an FBI agent and a cybersecurity expert must unravel an ever-growing web of political conspiracies.

Follows Nicolas Shaw, a retired U.S. special operative who becomes part of an elite "invisible" team that quietly takes out the worst villains around the world.

Ed Hemsler spends his life preparing for a disaster that may never come. Ronnie Meisner spends her life shopping for things she may never use. These two people will try to find love.